A genetic disorder is a medical condition caused by one or more gene mutations. A chromosomal abnormality or a mutation in a single gene (monogenic) or numerous genes (polygenic) might cause it. Because of the high number of genetic abnormalities, one out of every twenty-one people is affected with a "rare" genetic disorder (usually defined as affecting less than 1 in 2,000 people). The majority of genetic diseases are rare in and of themselves. The incidence of rare diseases is used to define them rather than unifying pathological or clinical criteria. Rare diseases cover a wide range of pathologies and pathogenesis mechanisms since they are distinguished by their low prevalence. Rare genetic diseases serve as a springboard for uncovering novel biology that has far-reaching implications for common human disorders. Changes in DNA are implicated in the cause of around 80% of rare disorders. Even if the symptoms aren't constantly evident, many diseases are present throughout a person's life.
Title : The foundation for rare disease and its role in the european rare disease research landscape
Daniel Scherman, Foundation for Rare Diseases, France
Title : The effect of Eupalinolide B on amyotrophic lateral sclerosis: A case report
Wang Huaixiu, Shanxi Provincial Hospital, China
Title : Progress related in genetic research on kawasaki disease
Jiao Fuyong, Shaanxi Provincial People’s Hospital, China
Title : Covid-19 seems to be Initiated by the heparan-sulfate dysregulation by coronavirus: The use of low-molecular- weight heparin (LMWH) can prevent and treat covid-19 when it Is used in early stages, as a heparan-sulfate-regulating medicine
Fereshteh Sedaghat, Sedaghat Memory Clinic, Iran (Islamic Republic of)
Title : Lumevoq gene therapy in leber hereditary optic neuropathy
Magali Taiel, GenSight Biologics, France
Title : Drug recommendation system using a collaborative filtering in machine learning
J. Somasekar, Jain University, India